Over the years, cutting edge tools, technologies and approaches have been implemented to increase understanding of the bovine immune system and mechanisms of pathogen control. Despite limited funding, compared to human immunological research, ILRAD/ILRI have made tremendous progress in bovine immunological research which remains a research focus at ILRI.
This project proposes a new strategy for creating resistance in cattle to African trypanosomiasis, a major disease that affects agricultural production in broad regions of Africa. The long-term aim is to generate genetically modified cattle, which carry a gene that imparts resistance to African trypanosomes.
Abstract African bovine trypanosomiasis caused by Trypanosoma sp., is a major constraint on cattle productivity in sub-Saharan Africa. Some African Bos taurus breeds are highly tolerant of infection, but the potentially more productive Bos indicus zebu breeds are much more susceptible. Zebu cattle are well adapted for plowing and haulage, and increasing their tolerance of …
A video illustrating the collaborative work between the International Livestock Research Institute (ILRI) scientists and their international partners in identifying 2 genes that convey resistance in livestock for trypanosomiasis